Prediction of HLA binding for verified candidates

Associated Tutorial

This workflows is part of the tutorial Neoantigen 6: Predicting HLA Binding, available in the GTN

Features

• Includes a Galaxy Workflow Report

Thanks to...

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Precision HLA typing from next-generation sequencing data.

Precision HLA typing from next-generation sequencing data using OptiType.

Table of Contents

Introduction Quick Start

With Docker With Singularity

Documentation Pipeline DAG

Input fastq Input bam

Credits

Introduction

OptiType is a HLA genotyping algorithm based on integer linear programming. Reads of whole exome/genome/transcriptome sequencing data are mapped against a reference of known MHC class I alleles. To produce accurate 4-digit HLA genotyping predictions, all major and minor HLA-I loci are ...